Antioxidant
The antioxidant activities of tocotrienols are mediated through induction of various antioxidant enzymes, such as superoxide dismutase and glutathione peroxidase. Tocotrienols reduce oxidative protein damage and lipid oxidation.
Anti-inflammatory activity
Research suggests that tocotrienols exhibit potent anti-inflammatory activity. Tocotrienols have been shown to suppress the expression of tumour necrosis factor-alpha (TNF-α), interleukins, inducible nitric oxide synthase, and cyclo-oxygenase 2 (COX-2), all of which have been shown to be involved with inflammation.
Healthy cholesterol
Tocotrienols have cholesterol-lowering properties. The mechanism of action is via inhibition of HMG-CoA reductase, an enzyme that is involved with the synthesis of cholesterol.
Reference: McEwen B. Vitamin E Tocotrienols: the next generation antioxidant and anti-inflammatory nutrient. JATMS 2019; 25(4): 204-206
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Suggested TGA Permitted Indication
- Antioxidant. Reduce free radicals formed in the body
- Helps reduce and decrease free radical damage to body cells
- Anti-inflammatory. Relieves inflammation
- Helps maintain and support healthy cholesterol